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RAS-induced transformation of mammary epithelial cells relies on ZEB1-dependent cellular reprogramming via a paracrine process

Hadrien de Blander , Laurie Tonon , Frédérique Fauvet , Roxane M Pommier , Christelle Lamblot , et al.
Preprints, Working Papers, ... hal-03800148v1

Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma

Antonin Tortereau , Nadège Milhau , Elodie Rhumy , Marie Castets , Frédérique Ponce , et al.
Veterinary Sciences, 2022, 9 (9), pp.494. ⟨10.3390/vetsci9090494⟩
Journal articles hal-03808606v1
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Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust , et al.
Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩
Journal articles hal-03711790v1
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Hepatic inflammation elicits production of proinflammatory netrin‐1 through exclusive activation of translation

Romain Barnault , Claire Verzeroli , Carole Fournier , Maud Michelet , Anna Rita Redavid , et al.
Hepatology, 2022, 76 (5), pp.1345-1359. ⟨10.1002/hep.32446⟩
Journal articles hal-03864005v1
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Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1

Simon Renders , Arthur Flohr Svendsen , Jasper Panten , Nicolas Rama , Maria Maryanovich , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-020-20801-0⟩
Journal articles hal-03428982v1
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Dependence receptors: new targets for cancer therapy

Morgan Brisset , Mélodie Grandin , Agnès Bernet , Patrick Mehlen , Frédéric Hollande
EMBO Molecular Medicine, 2021, 13 (11), ⟨10.15252/emmm.202114495⟩
Journal articles hal-03456446v1
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Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity

Yan Sun , Ambroise Manceau , Lisa Frydman , Lucie Cappuccio , David Neves , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (36), pp.e2103319118. ⟨10.1073/pnas.2103319118⟩
Journal articles hal-03357293v1
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A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis

Davide Pradella , Gianluca Deflorian , Alex Pezzotta , Anna Di Matteo , Elisa Belloni , et al.
Nature Communications, 2021, 12 (1), pp.4872. ⟨10.1038/s41467-021-24998-6⟩
Journal articles hal-03357307v1
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Cancer Microenvironment: Netrin-4 regulates stiffness and metastasis

Patrick Mehlen , Laurent Fattet
Nature Materials, 2021, 20 (6), pp.722-723. ⟨10.1038/s41563-021-01012-4⟩
Journal articles hal-03808576v1
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Targeting netrin‐3 in small cell lung cancer and neuroblastoma

Shan Jiang , Mathieu Richaud , Pauline Vieugué , Nicolas Rama , Jean‐guy Delcros , et al.
EMBO Molecular Medicine, 2021, 13 (4), ⟨10.15252/emmm.202012878⟩
Journal articles hal-03410529v1
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Immune checkpoint inhibitor treatment of a first cancer is associated with a decreased incidence of second primary cancer

P. Heudel , S. Chabaud , D. Perol , A. Flechon , J. Fayette , et al.
ESMO Open, 2021, 6 (1), pp.100044. ⟨10.1016/j.esmoop.2020.100044⟩
Journal articles hal-03808637v1
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RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas

Angela R Garcia-Rendueles , Miguel Chenlo , Fernando Oroz-Gonjar , Antonia Solomou , Anisha Mistry , et al.
Oncogene, 2021, 40 (45), pp.6354-6368. ⟨10.1038/s41388-021-02009-8⟩
Journal articles hal-03456432v1

Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features

Mélissa Jasmin , Eun Hee Ahn , Merja Voutilainen , Joanna Fombonne , Catherine Guix , et al.
EMBO Journal, 2020, ⟨10.15252/embj.2020105537⟩
Journal articles hal-03102123v1

BDNF and Netrin-1 repression by C/EBPβ in the gut triggers Parkinson’s disease pathologies, associated with constipation and motor dysfunctions

Eun Hee Ahn , Seong Su Kang , Xia Liu , Xuebing Cao , Soo Young Choi , et al.
Progress in Neurobiology, 2020, pp.101905. ⟨10.1016/j.pneurobio.2020.101905⟩
Journal articles hal-03102128v1
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CDYL2 Epigenetically Regulates MIR124 to Control NF-kB/STAT3-Dependent Breast Cancer Cell Plasticity

Maha Siouda , Audrey D Dujardin , Laetitia Barbollat-Boutrand , Marco Mendoza-Parra , Benjamin Gibert , et al.
iScience, 2020, 23 (6), pp.101141. ⟨10.1016/j.isci.2020.101141⟩
Journal articles hal-02956108v1

Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration

Jason Charish , Alireza Shabanzadeh , Danian Chen , Patrick Mehlen , Santhosh Sethuramanujam , et al.
Journal of Clinical Investigation, 2020, 130 (4), pp.2054-2068. ⟨10.1172/JCI125898⟩
Journal articles hal-03102140v1

Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling

Aurélia Huyghe , Giacomo Furlan , Duygu Ozmadenci , Christina Galonska , Jocelyn Charlton , et al.
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Journal articles hal-03102136v1

Netrin-1 and Its Receptor DCC Are Causally Implicated in Melanoma Progression

Amina Boussouar , Antonin Tortereau , Ambroise Manceau , Andrea Paradisi , Nicolas Gadot , et al.
Cancer Research, 2020, 80 (4), pp.747-756. ⟨10.1158/0008-5472.CAN-18-1590⟩
Journal articles hal-02493700v1
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Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis

Pierre-Antoine Bissey , Pauline Mathot , Catherine Guix , Mélissa Jasmin , Isabelle Goddard , et al.
Cancer Research, 2020, 80 (10), pp.1970-1980. ⟨10.1158/0008-5472.CAN-19-1340⟩
Journal articles hal-03102147v1

ctDNA in neuroendocrine carcinoma of gastroenteropancreatic origin or of unknown primary: the CIRCAN-NEC pilot study

Laura Gerard , Jessica Garcia , Arnaud Gauthier , Jonathan Lopez , Alice Durand , et al.
Neuroendocrinology, In press, ⟨10.1159/000512502⟩
Journal articles hal-02999436v1
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Actualités en recherche en oncologie : l'essentiel du 4e Symposium International 2019 du Centre de Recherche en Cancérologie de Lyon

Frédéric Catez , Nicole Dalla Venezia , Jean-Jacques Diaz , Bertrand Dubois , Anthony Ferrari , et al.
Bulletin du Cancer, 2020, 107 (1), pp.136-140. ⟨10.1016/j.bulcan.2019.12.002⟩
Journal articles hal-03004269v1

Cancer-Associated Fibroblasts Produce Netrin-1 to Control Cancer Cell Plasticity

Pei-Ju Sung , Nicolas Rama , Jeromine Imbach , Stephany Fiore , Benjamin Ducarouge , et al.
Cancer Research, 2019, 79 (14), pp.3651-3661. ⟨10.1158/0008-5472.CAN-18-2952⟩
Journal articles hal-02323505v1

The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death

Jonathan Vial , Amélie Royet , Philippe Cassier , Antonin Tortereau , Sarah Dinvaut , et al.
Cell Death and Differentiation, 2019, 26, pp.443-454. ⟨10.1038/s41418-018-0128-1⟩
Journal articles hal-01960268v1
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Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance

Juan Antonio Moreno-Bravo , Sergi Roig Puiggros , Patrick Mehlen , Alain Chédotal
Neuron, 2019, 101 (4), pp.625-634.e3. ⟨10.1016/j.neuron.2018.12.024⟩
Journal articles hal-02340095v1