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Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

Andrey A Yurchenko , Fatemeh Rajabi , Tirzah Braz-Petta , Hiva Fassihi , Alan Lehmann , et al.
Nature Communications, 2023, 14 (1), pp.2561. ⟨10.1038/s41467-023-38311-0⟩
Journal articles hal-04187974v1
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Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial

Fernanda Mosele , Elise Deluche , Amelie Lusque , Loïc Le Bescond , Thomas Filleron , et al.
Nature Medicine, 2023, 29 (8), pp.2110 - 2120. ⟨10.1038/s41591-023-02478-2⟩
Journal articles hal-04187928v1

Firing of Replication Origins Is Disturbed by a CDK4/6 Inhibitor in a pRb-Independent Manner

Su-Jung Kim , Chrystelle Maric , Lina-Marie Briu , Fabien Fauchereau , Giuseppe Baldacci , et al.
International Journal of Molecular Sciences, 2023, 24 (13), pp.10629. ⟨10.3390/ijms241310629⟩
Journal articles hal-04174634v1
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Congenital mirror movements are associated with defective polymerization of RAD51

Oriane Trouillard , Pauline Dupaigne , Margaux Dunoyer , Mohamed Doulazmi , Morten Krogh Herlin , et al.
Journal of Medical Genetics, 2023, pp.jmg-2023-109189. ⟨10.1136/jmg-2023-109189⟩
Journal articles hal-04136436v1

Proteogenomic Characterization of Bladder Cancer Reveals Sensitivity to Apoptosis Induced by Tumor Necrosis Factor–related Apoptosis-inducing Ligand in FGFR3-mutated Tumors

Clarice Groeneveld , Virginia Sanchez-Quiles , Florent Dufour , Mingjun Shi , Florent Dingli , et al.
European Urology, 2023, ⟨10.1016/j.eururo.2023.05.037⟩
Journal articles hal-04158903v1

Structural analysis of the Candida albicans mitochondrial DNA maintenance factor Gcf1p reveals a dynamic DNA-bridging mechanism

Aleix Tarrés-Solé , Federica Battistini , Joachim Gerhold , Olivier Piétrement , Belén Martínez-García , et al.
Nucleic Acids Research, 2023, ⟨10.1093/nar/gkad397⟩
Journal articles hal-04120278v1
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Mistimed origin licensing and activation stabilize common fragile sites under tight DNA-replication checkpoint activation

Olivier Brison , Stefano Gnan , Dana Azar , Stéphane Koundrioukoff , Rodrigo Melendez Garcia , et al.
Nature Structural and Molecular Biology, 2023
Journal articles hal-04070726v1
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The role of NEIL3 DNA glycosylase in the resistance to cisplatin

Umit Aliyaskarova
Molecular biology. Université Paris-Saclay, 2022. English. ⟨NNT : 2022UPASL104⟩
Theses tel-04132226v1

Aberrant DNA repair is a vulnerability in histone H3.3-mutant brain tumors

Beatrice Rondinelli , Giulia Giacomini , Sandra Piquet , Odile Chevallier , Juliette Dabin , et al.
Preprints, Working Papers, ... hal-03871540v1

Assembly mechanism and cryoEM structure of RecA recombination nucleofilaments from Streptococcus pneumoniae

Hertzog Maud , Perry Thomas Noé , Dupaigne Pauline , Serres Sandra , Morales Violette , et al.
Preprints, Working Papers, ... hal-03872288v1

Human RAD52 stimulates the RAD51-mediated homology search

Ali Akbar Muhammad , Thibault Peterlini , José Guirouilh-Barbat , Xavier Veaute , Didier Busso , et al.
Preprints, Working Papers, ... hal-03853674v1

In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

Gabriel Matos-Rodrigues , Vilma Barroca , Ali-Akbar Muhammad , Awatef Allouch , Stephane Koundrioukoff , et al.
Preprints, Working Papers, ... hal-03853667v1

The mechanism of damage recognition by apurinic/apyrimidinic endonuclease Nfo from Escherichia coli

Svetlana Senchurova , Victoria Syryamina , Aleksandra Kuznetsova , Darya Novopashina , Alexander Ishchenko , et al.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2022, 1866 (11), pp.130216. ⟨10.1016/j.bbagen.2022.130216⟩
Journal articles hal-03858612v1

Predicting immunotherapy outcomes in patients with MSI tumors using NLR and CT global tumor volume

Younes Belkouchi , Laetitia Nebot-Bral , Littisha Lawrance , Michele Kind , Clémence David , et al.
Frontiers in Oncology, 2022, 12, ⟨10.3389/fonc.2022.982790⟩
Journal articles hal-03907576v1

Palbociclib interferes with replication origin firing in a pRb independent manner

Su-Jung Kim , Chrystelle Maric , Lina-Marie Briu , Fabien Fauchereau , Giuseppe Baldacci , et al.
Preprints, Working Papers, ... hal-03809988v1
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Minors at risk of von Hippel-Lindau disease: 10 years’ experience of predictive genetic testing and follow-up adherence

Roseline Vibert , Khadija Lahlou-Laforêt , Maryam Samadi , Valérie Krivosic , Thomas Blanc , et al.
European Journal of Human Genetics, 2022, 30 (10), pp.1171-1177. ⟨10.1038/s41431-022-01157-z⟩
Journal articles inserm-03940490v1

The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli

Svetlana Senchurova , Aleksandra Kuznetsova , Alexander Ishchenko , Murat Saparbaev , Olga Fedorova , et al.
Cells, 2022, 11 (19), pp.2998. ⟨10.3390/cells11192998⟩
Journal articles hal-03859374v1

Safeguarding DNA Replication: A Golden Touch of MiDAS and Other Mechanisms

Baraah Al Ahmad Nachar , Filippo Rosselli
International Journal of Molecular Sciences, 2022, 23 (19), pp.11331. ⟨10.3390/ijms231911331⟩
Journal articles hal-03862560v1
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Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

Yann Benureau , Caroline Pouvelle , Pauline Dupaigne , Sonia Baconnais , Eliana Moreira Tavares , et al.
Nucleic Acids Research, 2022, 50 (17), pp.9909 - 9929. ⟨10.1093/nar/gkac746⟩
Journal articles hal-03853540v1
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The orchestration of NHEJ factors at DNA double-strand breaks by the Ku70/Ku80 heterodimer

M. Seif El Dahan , A.K. Stavridi , P. Frit , S. Baconnais , E. Le Cam , et al.
33rd European Crystallography Meeting, Aug 2022, Versailles, France. pp.e4-e4, ⟨10.1107/S2053273322096668⟩
Conference papers hal-04049201v1
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Strategies for Radioiodine Treatment: What’s New

Clotilde Sparano , Sophie Moog , Julien Hadoux , Corinne Dupuy , Abir Al Ghuzlan , et al.
Journal articles hal-03860250v1
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Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers

Laetitia Nebot-Bral , Antoine Hollebecque , Andrey A Yurchenko , Louise de Forceville , Mathieu Danjou , et al.
Journal for Immunotherapy of Cancer, 2022, 10, pp.e005059. ⟨10.1136/jitc-2022-005059⟩
Journal articles hal-03853375v1

Targeting genome integrity dysfunctions impedes metastatic potency in non–small cell lung cancer circulating tumor cell–derived explants

Tala Tayoun , Vincent Faugeroux , Marianne Oulhen , Olivier Déas , Judith Michels , et al.
JCI Insight, 2022, 7 (11), ⟨10.1172/jci.insight.155804⟩
Journal articles hal-03852545v1
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Redox Homeostasis in Thyroid Cancer: Implications in Na+/I− Symporter (NIS) Regulation

Juliana Cazarin , Corinne Dupuy , Denise Pires de Carvalho
International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms23116129⟩
Journal articles hal-03860293v1

SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells

Hugo Dorison , Ibtissam Talhaoui , Gerard Mazón
PLoS Genetics, 2022, 18 (3), pp.e1009860. ⟨10.1371/journal.pgen.1009860⟩
Journal articles hal-03855330v1
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SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells

Hugo Dorison , Ibtissam Talhaoui , Gerard Mazón
PLoS Genetics, 2022, 18 (3), pp.e1009860. ⟨10.1371/journal.pgen.1009860⟩
Journal articles inserm-03682251v1
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RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function

Ayeong So , Elodie Dardillac , Ali Muhammad , Catherine Chailleux , Laura Sesma-Sanz , et al.
Nucleic Acids Research, 2022, 50 (5), pp.2651-2666. ⟨10.1093/nar/gkac073⟩
Journal articles hal-03812119v1

A new frontier in Fanconi anemia: From DNA repair to ribosome biogenesis

Anna Gueiderikh , Frédérique Maczkowiak-Chartois , Filippo Rosselli
Blood Reviews, 2022, 52, pp.100904. ⟨10.1016/j.blre.2021.100904⟩
Journal articles hal-03862574v1
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Anaplastic Thyroid Carcinoma: An Update

Arnaud Jannin , Alexandre Escande , Abir Al Ghuzlan , Pierre Blanchard , Dana Hartl , et al.
Journal articles hal-03859894v1
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XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil

Ligia Pereira Castro , Danilo Batista-Vieira , Tiago Antonio de Souza , Ana Rafaela de Souza Timoteo , Jessica Dayanna Landivar Coutinho , et al.
Frontiers in Genetics, 2022, 12, ⟨10.3389/fgene.2021.784963⟩
Journal articles hal-03853572v1