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Impact of Molecular Biology in Diagnosis, Prognosis, and Therapeutic Management of BCR::ABL1-Negative Myeloproliferative Neoplasm

Norman Abbou , Pauline Piazzola , Jean Gabert , Vincent Ernest , Robin Arcani , et al.
Cells, 2023, 12 (1), pp.105. ⟨10.3390/cells12010105⟩
Journal articles hal-03935016v1
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Adrenomedullin Secreted by Melanoma Cells Promotes Melanoma Tumor Growth through Angiogenesis and Lymphangiogenesis

Zohra Benyahia , Caroline Gaudy-Marqueste , Caroline Berenguer-Daizé , Norhimane Chabane , Nadège Dussault , et al.
Cancers, 2022, 14 (23), pp.5909. ⟨10.3390/cancers14235909⟩
Journal articles hal-03882558v1

1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastases

P. Métellus , C. Camilla , E. Bialecki , N. Beaufils , C. Vellutini , et al.
Annals of Oncology, 2022, 33, pp.S1314. ⟨10.1016/j.annonc.2022.07.1771⟩
Journal articles hal-03982168v1
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1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastases

Philippe Metellus , Clara Camilla , Emilie Bialecki , Nathalie Beaufils , Christine Vellutini , et al.
Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), Sep 2022, PARIS, France. 33, pp.S1314, 2022, ⟨10.1016/j.annonc.2022.07.1771⟩
Conference poster hal-03955526v1
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Deep Learning Architecture Optimization with Metaheuristic Algorithms for Predicting BRCA1/BRCA2 Pathogenicity NGS Analysis

Eric Pellegrino , Theo Brunet , Christel Pissier , Clara Camilla , Norman Abbou , et al.
BioMedInformatics, 2022, 2 (2), pp.244-267. ⟨10.3390/biomedinformatics2020016⟩
Journal articles hal-03660599v1
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Machine learning random forest for predicting oncosomatic variant NGS analysis

Eric Pellegrino , Coralie Jacques , Nathalie Beaufils , Isabelle Nanni , Antoine Carlioz , et al.
Scientific Reports, 2021, 11 (1), pp.21820. ⟨10.1038/s41598-021-01253-y⟩
Journal articles hal-03430785v1
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Role of the Tyrosine Phosphatase SHP-2 in Mediating Adrenomedullin Proangiogenic Activity in Solid Tumors

Romain Sigaud , Nadège Dussault , Caroline Berenguer-Daize , Christine Vellutini , Zohra Benyahia , et al.
Frontiers in Oncology, 2021, 11, ⟨10.3389/fonc.2021.753244⟩
Journal articles hal-03400871v1

Molecular characterization of fast-growing melanomas

Caroline Gaudy-Marqueste , Nicolas Macagno , Anderson Loundou , Eric Pellegrino , L'Houcine Ouafik , et al.
Journal of The American Academy of Dermatology, 2021, ⟨10.1016/j.jaad.2021.07.011⟩
Journal articles hal-03401110v1

Identification of the chemical composition of six essential oils with mass spectroscopy and evaluation of their antibacterial and antioxidant potential

Imane Nait Irahal , Fatima Azzahra Lahlou , Fouzia Hmimid , Ahmed Errami , Ismail Guenaou , et al.
Flavour and Fragrance Journal, 2021, 36 (4), pp.465-476. ⟨10.1002/ffj.3657⟩
Journal articles hal-03603701v1

High incidence of CDA deficiency in patients with hematological malignancies: perspectives and therapeutic implications

M. Donnette , J. Ciccolini , C. Pissier , R. Costello , F. Duffaud , et al.
Annals of Oncology, 2021, 32 (5), pp.684-686. ⟨10.1016/j.annonc.2021.01.072⟩
Journal articles hal-03279253v1
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FP09.05 Driver Oncogenic Alterations and Indoor Radon in NSCLC Patients From the IFCT Biomarker Cohort: Bioradon France Study

L. Mezquita , F. Barlesi , G. Ielsch , J. Merlio , D. Debieuvre , et al.
Journal of Thoracic Oncology, 2021, 16 (3), pp.S214. ⟨10.1016/j.jtho.2021.01.122⟩
Journal articles hal-03603784v1
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Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy

Ramiro Vázquez , Maria E Riveiro , Caroline Berenguer-Daize , Anthony O’kane , Julie Gormley , et al.
Frontiers in Oncology, 2021, 10, ⟨10.3389/fonc.2020.589218⟩
Journal articles hal-03105775v1
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PTEN, ATM, IDH1 mutations and MAPK pathway activation as modulators of PFS and OS in patients treated by first line EGFR TKI, an ancillary study of the French Cooperative Thoracic Intergroup (IFCT) Biomarkers France project

H. Blons , J.-B. Oudart , J.-P. Merlio , D. Debieuvre , F. de Fraipont , et al.
Lung Cancer, 2021, 151, pp.69-75. ⟨10.1016/j.lungcan.2020.11.008⟩
Journal articles hal-03105761v1

Cytoprotective effect of ethyl acetate fraction from Ephedra fragilis on H2O2-induced oxidative damage in Tetrahymena pyriformis

Ismail Guenaou , Fouzia Hmimid , Fatima Azzahra Lahlou , Ahmed Errami , Imane Nait Irahal , et al.
Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 2021, 239, pp.108899. ⟨10.1016/j.cbpc.2020.108899⟩
Journal articles hal-03279242v1
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Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study

Pascale Tomasini , Fabrice Barlesi , Sophie Gilles , Isabelle Nanni-Metellus , Riccardo Soffietti , et al.
Oncotarget, 2020, 11 (50), pp.4648-4654. ⟨10.18632/oncotarget.27837⟩
Journal articles hal-03105754v1
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Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes

Anne-Marie Ruppert , Michèle Beau-Faller , Didier Debieuvre , L'Houcine Ouafik , Virginie Westeel , et al.
Jto Clinical and Research Reports, 2020, 1 (3), pp.100052. ⟨10.1016/j.jtocrr.2020.100052⟩
Journal articles hal-03430888v1
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Adrenomedullin Blockade Induces Regression of Tumor Neovessels through Interference with Vascular Endothelial- Cadherin Signalling

Ghizlane Khalfaoui-Bendriss , Nadège Dussault , Samantha Fernandez-Sauze , Caroline Berenguer-Daize , Romain Sigaud , et al.
Prime Archives in Cancer Research 1st edition, 2020, 978-81-944664-4-4
Book sections hal-02955254v1
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Inequity in access to personalized medicine in France: Evidences from analysis of geo variations in the access to molecular profiling among advanced non-small-cell lung cancer patients: Results from the IFCT Biomarkers France Study

Samuel Kembou Nzale , William B Weeks , L’houcine Ouafik , Isabelle Rouquette , Michèle Beau-Faller , et al.
PLoS ONE, 2020, 15 (7), pp.e0234387. ⟨10.1371/journal.pone.0234387⟩
Journal articles hal-02888579v1
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Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project

Michèle Beau-Faller , Erwan Pencreach , Charlotte Leduc , Hélène Blons , Jean-Philippe Merlio , et al.
Lung Cancer, 2020, 140, pp.19-26. ⟨10.1016/j.lungcan.2019.10.013⟩
Journal articles hal-02483277v1

Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project

Michèle Beau-Faller , Erwan Pencreach , Charlotte Leduc , Hélène Blons , Jean-Philippe Merlio , et al.
Lung Cancer, 2020, 140, pp.19-26. ⟨10.1016/j.lungcan.2019.10.013⟩
Journal articles hal-02504797v1
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Simultaneous determination of cytosine arabinoside and its metabolite uracil arabinoside in human plasma by LC-MS/MS: Application to pharmacokinetics-pharmacogenetics pilot study in AML patients

Mélanie Donnette , Caroline Solas , Madeleine Giocanti , Geoffroy Venton , Laure Farnault , et al.
Journal of Chromatography B Biomedical Sciences and Applications, 2019, 1126-1127, pp.121770. ⟨10.1016/j.jchromb.2019.121770⟩
Journal articles hal-02483206v1

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

Gianluca Civenni , Roberto Bosotti , Andrea Timpanaro , Ramiro Vàzquez , Jessica Merulla , et al.
Cell Metabolism, 2019, 30 (2), pp.303-318.e6. ⟨10.1016/j.cmet.2019.05.004⟩
Journal articles hal-02483099v1

Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiency

Crescent Gbeto , Sylvie Quaranta , Roxane Mari , Raphaelle Fanciullino , Catherine Roche , et al.
Pharmacogenomics, 2019, 20 (13), pp.931-938. ⟨10.2217/pgs-2019-0028⟩
Journal articles hal-02483216v1

Clinical outcomes of non–small-cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France study

Sébastien Couraud , Fabrice Barlesi , Clara Fontaine-Deraluelle , Didier Debieuvre , Jean-Philippe Merlio , et al.
European Journal of Cancer, 2019, 116, pp.86-97. ⟨10.1016/j.ejca.2019.04.016⟩
Journal articles hal-02483130v1
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Efficacy of Immune Checkpoint Inhibitors in KRAS-Mutant Non-Small Cell Lung Cancer (NSCLC)

Arnaud Jeanson , Pascale Tomasini , Maxime Souquet-Bressand , Nicolas Brandone , Mohamed Boucekine , et al.
Journal of Thoracic Oncology, 2019, 14 (6), pp.1095-1101. ⟨10.1016/j.jtho.2019.01.011⟩
Journal articles hal-02104417v1
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Using Digital Droplet Polymerase Chain Reaction to Detect the Mosaic GNAS Mutations in Whole Blood DNA or Circulating Cell-Free DNA in Fibrous Dysplasia and McCune-Albright Syndrome

Pauline Romanet , Pascal Philibert , Frederic Fina , Thomas Cuny , Catherine Roche , et al.
The Journal of Pediatrics, 2018
Journal articles hal-01975613v1

Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluid

Diane Frankel , Isabelle Nanni-Metellus , Andrée Robaglia-Schlupp , Pascale Tomasini , Julien Guinde , et al.
Clinical Chemistry and Laboratory Medicine, 2018, 56 (5), pp.748 - 753. ⟨10.1515/cclm-2017-0527⟩
Journal articles hal-01769686v1
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CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine

Raphaelle Fanciullino , Laure Farnault , Mélanie Donnette , Diane-Charlotte Imbs , Catherine Roche , et al.
Blood Advances, 2018, 2 (5), pp.462 - 469. ⟨10.1182/bloodadvances.2017014126⟩
Journal articles hal-01770057v1
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Proof of concept: prognostic value of the plasmatic concentration of circulating cell free DNA in desmoid tumors using ddPCR

Nicolas Macagno , Frédéric Fina , Nicolas Penel , Corinne Bouvier , Isabelle Nanni , et al.
Oncotarget, 2018, 9 (26), pp.18296-18308. ⟨10.18632/oncotarget.24817⟩
Journal articles hal-01794155v1

EGFR tyrosine kinase inhibitors versus chemotherapy in EGFR wild-type pre-treated advanced nonsmall cell lung cancer in daily practice

Pascale Tomasini , Solenn Brosseau , Julien Mazières , Jean Merlio , Michèle Beau-Faller , et al.
European Respiratory Journal, 2017, 50 (2), pii: 1700514. ⟨10.1183/13993003.00514-2017⟩
Journal articles hal-01699297v1