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Global citizen deliberation on genome editing

John Dryzek , Dianne Nicol , Simon Niemeyer , Sonya Pemberton , Nicole Curato , et al.
Science, 2020, 369 (6510), pp.1435-1437. ⟨10.1126/science.abb5931⟩
Journal articles hal-04023818v1
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LifeTime and improving European healthcare through cell-based interceptive medicine

Nikolaus Rajewsky , Geneviève Almouzni , Stanislaw A Gorski , Stein Aerts , Ido Amit , et al.
Nature, 2020, 587, pp.377 - 386. ⟨10.1038/s41586-020-2715-9⟩
Journal articles hal-04023884v1

ERK-mediated loss of miR-199a-3p and induction of EGR1 act as a "toggle switch" of GBM cell dedifferentiation into NANOG- and OCT4-positive cells

Fabien Almairac , Laurent Turchi , Nathalie Sakakini , David Debruyne , Sarah Elkeurti , et al.
Cancer Research, 2020, 80, pp.3236-3250. ⟨10.1158/0008-5472.CAN-19-0855⟩
Journal articles hal-02890919v1

Covid-19 : protocoles de soins ou protocoles de recherche ?

Philippe Amiel , Hervé Chneiweiss , Christine Dosquet
Médecine/Sciences, 2020, 36 (5), pp.521-523. ⟨10.1051/medsci/2020107⟩
Journal articles hal-02877389v1
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Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

Mirca S Saurty-Seerunghen , Léa Bellenger , Elias El-Habr , Virgile Delaunay , Delphine Garnier , et al.
Acta Neuropathologica Communications, 2019, 7 (1), pp.155. ⟨10.1186/s40478-019-0819-y⟩
Journal articles hal-02344991v1
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Clinical Research: Access to Potential Participants Pre-Enrollment: Staying One Step Ahead?

François Eisinger , François Hirsch , Bernard Baertschi , Mylène Botbol-Baum , Isabelle Remy-Jouet , et al.
Other publications inserm-02393894v1
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ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

Dalal Bakhos-Douaihy , Chantal Desmaze , Maya Jeitany , Laurent Gauthier , Denis Biard , et al.
Oncogene, 2019, 10 (7), pp.773-784. ⟨10.18632/oncotarget.26616⟩
Journal articles hal-03941150v1
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WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3 cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

Wanyin Chen , Leonel Nguekeu Zebaze , Jihu Dong , Laëtitia Chezeau , Perrine Inquimbert , et al.
Oncotarget, 2018, 9 (43), pp.27197-27219. ⟨10.18632/oncotarget.25509⟩
Journal articles hal-02349611v1
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The tsunami named CRISPR/Cas9

H. Chneiweiss
Revue Neurologique, 2018, 174 (7-8), pp.487-488. ⟨10.1016/j.neurol.2018.04.006⟩
Journal articles hal-01799815v1
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Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation

Paul Lesueur , François Chevalier , Elias A. El-Habr , Marie-Pierre Junier , Hervé Chneiweiss , et al.
Scientific Reports, 2018, 8, pp.3664. ⟨10.1038/s41598-018-22022-4⟩
Journal articles hal-01738585v1
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Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma

Erika COSSET , Sten Ilmjärv , Valérie Dutoit , Kathryn Elliott , Tami von Schalscha , et al.
Cancer Cell, 2017, 32, pp.856 - 868.e5. ⟨10.1016/j.ccell.2017.10.016⟩
Journal articles hal-04021422v1

DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression

David N. Debruyne , Laurent Turchi , Fanny Burel-Vandenbos , Mohamed Fareh , F Almairac , et al.
Oncogene, 2017, 37 (2), pp.241-254. ⟨10.1038/onc.2017.323⟩
Journal articles hal-01984521v1

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling

Jihu Dong , Francisco J Aulestia , Suzana Assad Kahn , Maria Zeniou , Luiz Gustavo Dubois , et al.
BBA - Biochimica et Biophysica Acta, 2017, 1864 (6), pp.1018-1027. ⟨10.1016/j.bbamcr.2017.01.010⟩
Journal articles hal-01546102v1

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance

Maya Jeitany , Dalal Bakhos-Douaihy , David C. Silvestre , Jose R. Pineda , Nicolas Ugolin , et al.
Oncotarget, 2017, 8 (16), pp.26269-26280. ⟨10.18632/oncotarget.15447⟩
Journal articles hal-01541412v1

Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth

Mohamed Fareh , Fabien Almairac , Laurent Turchi , Fanny Burel-Vandenbos , Philippe Paquis , et al.
Cell Death and Disease, 2017, 8 (3), pp.e2713. ⟨10.1038/cddis.2017.117⟩
Journal articles hal-01541413v1
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Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System

Miguel Marigil , Naiara Martinez-Velez , Pablo Domínguez , Miguel Angel Idoate , Enric Xipell , et al.
PLoS ONE, 2017, 12 (1), pp.e0170501. ⟨10.1371/journal.pone.0170501⟩
Journal articles hal-01478511v1

CRISPR-Cas9: A European position on genome editing

François Hirsch , Yves Lévy , Hervé Chneiweiss
Nature, 2017, 541 (7635), pp.30. ⟨10.1038/541030c⟩
Journal articles hal-01541414v1
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A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

Elias A El-Habr , Gustavo Luiz Dubois , Fanny Burel-Vandenbos , Alexandra Bogeas , Joanna Lipecka , et al.
Acta Neuropathologica, 2017, 133 (4), pp.645-660. ⟨10.1007/s00401-016-1659-5⟩
Journal articles inserm-01481051v1
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CHD7 promotes proliferation of neural stem cells mediated by MIF

Shigeki Ohta , Tomonori Yaguchi , Hironobu Okuno , Hervé Chneiweiss , Yutaka Kawakami , et al.
Molecular Brain, 2016, 9 (1), pp.96. ⟨10.1186/s13041-016-0275-6⟩
Journal articles inserm-01415337v1

Calcium signaling orchestrates glioblastoma development: Facts and conjunctures

Catherine Leclerc , Jacques Haeich , Francisco J. Aulestia , Marie-Claude Kilhoffer , Andrew L. Miller , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2016, 1863 (6, B, SI), pp.1447-1459. ⟨10.1016/j.bbamcr.2016.01.018⟩
Journal articles hal-01541419v1

Our students are talented!

Herve Chneiweiss
Médecine/Sciences, 2016, 32 (6-7), pp.537-538. ⟨10.1051/medsci/20163206002⟩
Journal articles hal-01541418v1

A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells

Fabrice Lopez , Philipe Paquis , Fabien Almairac , Denys Fontaine , Nathalie Baeza-Kallee , et al.
Journal of Biological Chemistry, 2016, 291 (20), pp.10684-10699. ⟨10.1074/jbc.M116.720698⟩
Journal articles hal-01460121v1

The biomedical research thought in french : New year, new concepts

Herve Chneiweiss
Médecine/Sciences, 2016, 32 (1), pp.7-8. ⟨10.1051/medsci/20163201001⟩
Journal articles hal-01541416v1

Differential thyroid hormone sensitivity of fast cycling progenitors in the neurogenic niches of tadpoles and juvenile frogs

L. Preau , K. Le Blay , E. Saint Paul , G. Morvan-Dubois , B. A. Demeneix
Molecular and Cellular Endocrinology, 2016, 420 (C), pp.138-151. ⟨10.1016/j.mce.2015.11.026⟩
Journal articles hal-01541415v1

Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression

Balbino L. Santos , Mona N. Oliveira , Paulo L. C. Coelho , Bruno P. S. Pitanga , Alessandra B. Da Silva , et al.
Chemico-Biological Interactions, 2015, 242, pp.123-138. ⟨10.1016/j.cbi.2015.07.014⟩
Journal articles hal-01541425v1
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Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

Stéphane Kerbrat , Benoit Vingert , Marie-Pierre Junier , Flavia Castellano , François Renault-Mihara , et al.
PLoS ONE, 2015, 10 (8), pp.e0136885. ⟨10.1371/journal.pone.0136885⟩
Journal articles hal-01235701v1
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Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells

Maria Zeniou , Marie Fève , Samir Mameri , Jihu Dong , Christophe Salomé , et al.
PLoS ONE, 2015, 10 (8), pp.e0134793. ⟨10.1371/journal.pone.0134793⟩
Journal articles hal-01223842v1

Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro

Fabio A. Mendes , Juliana M. Coelho Aguiar , Suzana A. Kahn , Alice H. Reis , Luiz Gustavo Dubois , et al.
PLoS ONE, 2015, 10 (8), pp.e0133689. ⟨10.1371/journal.pone.0133689⟩
Journal articles hal-01541426v1

An ethic of dialogue between science and society

Herve Chneiweiss
Médecine/Sciences, 2015, 31 (2), pp.40-42. ⟨10.1051/medsci/201531s111⟩
Journal articles hal-01541424v1
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A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT)

Maya Jeitany , Jose Ramon Pineda , Quingyuan Liu , Rosa Maria Porreca , Françoise Hoffschir , et al.
International Journal of Cancer, 2015, 136 (7), pp.1546-1558. ⟨10.1002/ijc.29171⟩
Journal articles hal-01143394v1