%0 Journal Article %T Subclinical BCG-osis in a Captive Badger (Meles meles) with Lymphoma %+ Animal and Plant Health Agency (APHA) %+ Animal and Plant Health Agency [Weybridge] (APHA) %+ Laboratoire de la rage et de la faune sauvage de Nancy (LRFSN) %+ Laboratoire de santé animale, sites de Maisons-Alfort et de Normandie %A Bianco, C. %A Lesellier, S. %A Barrat, J. %A Richomme, C. %A Boschiroli, M.-L. %A Núñez, A. %< avec comité de lecture %@ 0021-9975 %J Journal of Comparative Pathology %I Elsevier %V 176 %P 76-80 %8 2020-04 %D 2020 %R 10.1016/j.jcpa.2020.02.009 %K Bacillus %K Calmette–Guérin %K Badger %K Lymphoma %K Mycobacterium %Z Life Sciences [q-bio] %Z Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health %Z Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyJournal articles %X Subclinical systemic dissemination of Bacillus Calmette-Guérin (BCG) is described in a captive badger (Meles meles) with lymphoma. An adult female European badger was vaccinated per os with BCG and after 8 weeks post-mortem examination identified marked lymphadenomegaly and multinodular hepatic lesions. The histopathology and immunohistochemistry confirmed a multicentric T-cell lymphoma, associated with high BCG bacterial load in numerous tissues. The histology did not identify BCG-associated lesions. The scenario suggested that the T-cell lymphoma likely favoured the dissemination of the BCG ('BCG-osis'). Given that lymphoma is rare in badgers, this neoplasm should not interfere with the efficacy of large-scale vaccination programmes. %G English %L anses-03294027 %U https://anses.hal.science/anses-03294027 %~ ANSES %~ AGREENIUM %~ EMERGIN