%0 Journal Article %T The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7 %+ Institute of Ecology and Earth Sciences [Tartu] %+ University of Hohenheim %+ Sudan International University %+ World Health Organization Collaborating Centre for the Epidemiology, Detection and Control of Cystic and Alveolar Echinococcosis %+ Laboratoire de la rage et de la faune sauvage de Nancy (LRFSN) %+ University of Melbourne %+ Golestan University of Medical Sciences %+ Isfahan University of Medical Sciences %+ Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM) %+ Universidad Nacional del Comahue [Neuquén] (UNCOMA) %+ Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS) %+ Shahid Beheshti University of Medical Sciences [Tehran] (SBUMS) %+ Laboratorio de Zoonosis Parasitarias (FCEyN, UNMdP) %+ Dr. Manuel Gea González General Hospital %+ Instituto de Salud Carlos III [Madrid] (ISC) %+ Medical University of Warsaw - Poland %+ Polish Academy of Sciences (PAN) %+ Lithuanian University of Health Sciences [Kaunas, Lithuania] %+ Slovak Academy of Sciences (SAS) %+ I.I. Schmalhausen Institute of Zoology of NASU %A Laurimäe, Teivi %A Kinkar, Liina %A Romig, Thomas %A Omer, Rihab %A Casulli, Adriano %A Umhang, Gérald %A Gasser, Robin %A Jabbar, Abdul %A Sharbatkhori, Mitra %A Mirhendi, Hossein %A Ponce-Gordo, Francisco %A Lazzarini, Lorena %A Soriano, Silvia %A Varcasia, Antonio %A Rostami Nejad, Mohammad %A Andresiuk, Vanessa %A Maravilla, Pablo %A González, Luis Miguel %A Dybicz, Monika %A Gawor, Jakub %A Šarkūnas, Mindaugas %A Šnábel, Viliam %A Kuzmina, Tetiana %A Saarma, Urmas %Z Institutional research funding from the Estonian Ministry of Education and Research (IUT20-32) %Z The Estonian Doctoral School of Ecology and Environmental Sciences %< avec comité de lecture %Z LNR Echinococcus spp. %@ 1567-1348 %J Infection, Genetics and Evolution %I Elsevier %V 64 %P 85-94 %8 2018-10 %D 2018 %R 10.1016/j.meegid.2018.06.016 %M 29906638 %K Cystic echinococcosis %K Genotype G6 %K Genotype G7 %K Hydatid disease %K Mitochondrial genome %K Zoonosis %Z Life Sciences [q-bio] %Z Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology %Z Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal HealthJournal articles %X Cystic echinococcosis (CE) is a zoonotic disease caused by the larval stage of the species complex Echinococcus granulosus sensu lato. Within this complex, genotypes G6 and G7 have been frequently associated with human CE worldwide. Previous studies exploring the genetic variability and phylogeography of genotypes G6 and G7 have been based on relatively short mtDNA sequences, and the resolution of these studies has often been low. Moreover, using short sequences, the distinction between G6 and G7 has in some cases remained challenging. The aim here was to sequence complete mitochondrial genomes (mitogenomes) to obtain deeper insight into the genetic diversity, phylogeny and population structure of genotypes G6 and G7. We sequenced complete mitogenomes of 94 samples collected from 15 different countries worldwide. The results demonstrated that (i) genotypes G6 and G7 can be clearly distinguished when mitogenome sequences are used; (ii) G7 is represented by two major haplogroups, G7a and G7b, the latter being specific to islands of Corsica and Sardinia; (iii) intensive animal trade, but also geographical isolation, have likely had the largest impact on shaping the genetic structure and distribution of genotypes G6 and G7. In addition, we found phylogenetically highly divergent haplotype from Mongolia (Gmon), which had a higher affinity to G6. %G English %L anses-03419409 %U https://anses.hal.science/anses-03419409 %~ ANSES %~ OPENAIRE %~ AGREENIUM