%0 Journal Article %T Descriptive analyses of maternally-derived antibody levels against porcine circovirus 2 (PCV-2) in 3- and 21-day-old piglets from farms of four European countries using different vaccination protocols in sows %+ Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA) %+ Centre de Recerca en Sanitat Animal [UAB, Spain] (CReSA) %+ Laboratoire de Ploufragan-Plouzané-Niort [ANSES] %+ Veterinary Pig Practice Scheidegg %+ Università degli studi di Parma = University of Parma (UNIPR) %+ Zoetis %A Sibila, Marina %A Llorens Segales, Anna Maria %A Huerta, Eva %A Fablet, Christelle %A Faderl, Michael %A Ferrari, Luca %A Rose, Nicolas %A Palzer, Andreas %A Martelli, Paolo %A Venegas-Vargas, Maria, C. %A Fredrickson, Daniel %A Taylor, Lee %A Balasch, Monica %A Bandrick, Meggan %A Segalés, Joaquim %Z We are also grateful to CERCA Programme/Generalitat de Catalunya. %< avec comité de lecture %@ 2055-5660 %J Porcine health management %I BioMed Central %V 8 %N 1 %P 41 %8 2022-10-03 %D 2022 %R 10.1186/s40813-022-00284-9 %M 36192816 %K Porcine circovirus 2 %K Maternally-derived antibodies %K Sow vaccination %Z Life Sciences [q-bio]Journal articles %X Background: Up to now, information on the levels of maternally-derived antibodies (MDA) against PCV-2 in suckling piglets born to sows vaccinated with different strategies is scarce in the literature. In the present observational study, the PCV-2-specific MDA titres from piglets from 109 farms (thirty 3-day-old and thirty 21-day-old piglets per farm) across four different European countries (France n = 30, Germany n = 27, Italy n = 22 and Spain n = 30) using different sow vaccination strategies (during gestation, as a gilt, as a piglet or never) were assessed. Results: In all four countries, mean log PCV-2 MDA titres were higher in 3-day-old piglets than in the 3-week-old ones, being significant in most of all the comparisons performed. Within each country, the highest PCV-2-specific MDA titres were observed in the 3-day-old piglets born to sows vaccinated during gestation. Indeed, in the four countries, more than 60% of this subpopulation (3-day-old piglets from sows vaccinated during pregnancy) had the highest log PCV-2 titres detectable with the ELISA technique used in this study. The lowest MDA titres were more variable. Whereas in France and Germany the lowest titres corresponded to 21-day-old piglets born from sows vaccinated as a piglet, in Italy, they corresponded to 21-day-old piglets derived from sows vaccinated as a gilt and in Spain to 21-dayold piglets born from non-vaccinated sows. In this study, PCV-2-specific MDA titres at 3 and 21 days of age were not affected by sow parity. Conclusions: Data obtained could be considered as a European global overview of PCV-2-specific MDA titres present in the pre-vaccinated piglet populations in different European countries, with titres tending to be higher in younger piglets, but with values variable among countries and sow vaccination strategies. %G English %2 https://anses.hal.science/anses-03980596/document %2 https://anses.hal.science/anses-03980596/file/40813_2022_Article_284.pdf %L anses-03980596 %U https://anses.hal.science/anses-03980596 %~ ANSES %~ AGREENIUM