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Journal Articles Current Opinion in Food Science Year : 2022

Taking account of genomics in quantitative microbial risk assessment: what methods? what issues?

Abstract

The application of whole-genome sequencing (WGS) to the risk assessment of foodborne pathogens is a key challenge. WGS offers the highest level of strain discrimination for more precise hazard identification, hazard characterization, and exposure assessment, leading to deeper risk characterization. Genome-wide association studies represent today powerful tools for the identification of associations between genomic elements and microbial phenotypic properties. Other cutting-edge tools include machine learning or statistical methods to characterize phenotype distribution on a phylogenetic tree. A panorama of the available methods is presented as well as the specific issues associated with the application of these methods to phenotypes of interest for risk assessment.
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anses-03920741 , version 1 (15-05-2024)

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Laurent Guillier, Federica Palma, Lena Fritsch. Taking account of genomics in quantitative microbial risk assessment: what methods? what issues?. Current Opinion in Food Science, 2022, 48, pp.100922. ⟨10.1016/j.cofs.2022.100922⟩. ⟨anses-03920741⟩

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