Human biomonitoring guidance values (HBM-GVs) for priority substances under the HBM4EU initiative – New values derivation for deltamethrin and cyfluthrin and overall results - Anses - Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail Access content directly
Journal Articles International Journal of Hygiene and Environmental Health Year : 2023

Human biomonitoring guidance values (HBM-GVs) for priority substances under the HBM4EU initiative – New values derivation for deltamethrin and cyfluthrin and overall results

Abstract

The European Initiative HBM4EU aimed to further establish human biomonitoring across Europe as an important tool for determining population exposure to chemicals and as part of health-related risk assessments, thus making it applicable for policy advice. Not only should analytical methods and survey design be harmonized and quality assured, but also the evaluation of human biomonitoring data. For the health-related interpretation of the data within HBM4EU, a strategy for deriving health-based human biomonitoring guidance values (HBM-GVs) for both the general population and workers was agreed on. On this basis, HBM-GVs for exposure biomarkers of 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), phthalates (diethyl hexyl phthalate (DEHP), di-n-butyl phthalate (DnBP), diisobutyl phthalate (DiBP), butyl benzyl phthalate (BBzP), and bis-(2-propylheptyl) phthalate (DPHP)), bisphenols A and S, pyrethroids (deltamethrin and cyfluthrin), solvents (1-methyl-2-pyrrolidone (NMP), 1-ethylpyrrolidin-2-one (NEP), N-dimethylformamide (DMF), N,N-dimethylacetamide (DMAC)), the heavy metal cadmium and the mycotoxin deoxynivalenol (DON) were developed and assigned a level of confidence. The approach to HBM-GV derivations, results, and limitations in data interpretation with special focus on the pyrethroids are presented in this paper.
Fichier principal
Vignette du fichier
1-s2.0-S1438463922001808-main.pdf (1.39 Mo) Télécharger le fichier
Origin Publisher files allowed on an open archive

Dates and versions

anses-03963370 , version 1 (30-01-2023)

Identifiers

Cite

P. Apel, F. Lamkarkach, R. Lange, F. Sissoko, M. David, et al.. Human biomonitoring guidance values (HBM-GVs) for priority substances under the HBM4EU initiative – New values derivation for deltamethrin and cyfluthrin and overall results. International Journal of Hygiene and Environmental Health, 2023, 248, pp.114097. ⟨10.1016/j.ijheh.2022.114097⟩. ⟨anses-03963370⟩

Collections

ANSES
7 View
21 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More