MLST typing of Escherichia coli isolates overproducing AmpC {beta}-lactamase. - Anses - Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail Access content directly
Journal Articles Journal of Antimicrobial Chemotherapy Year : 2009

MLST typing of Escherichia coli isolates overproducing AmpC {beta}-lactamase.

A. Guillouzouic
  • Function : Author
N. Caroff
  • Function : Author
S. Dauvergne
  • Function : Author
D. Lepelletier
  • Function : Author
A. Reynaud
  • Function : Author
S. Corvec
  • Function : Author

Abstract

Escherichia coli is the major commensal aerobic bacterium of the digestive tract of humans and animals, but is also the most frequent human bacterial pathogen. As a consequence, resistance mechanisms carried by this species are of particular concern. One of these mechanisms is the overproduction of the chromosomal AmpC β-lactamase, leading to increased MICs of most β-lactams including third-generation cephalosporins. AmpC overproduction is caused by various mutations in the ampC promoter (–42, –32 and –11) increasing homology with the consensus promoter for RNA polymerase,

Dates and versions

hal-00405448 , version 1 (20-07-2009)

Identifiers

Cite

A. Guillouzouic, N. Caroff, S. Dauvergne, D. Lepelletier, Agnès Perrin-Guyomard, et al.. MLST typing of Escherichia coli isolates overproducing AmpC {beta}-lactamase.. Journal of Antimicrobial Chemotherapy, 2009, 63 (6), pp.1290-2. ⟨10.1093/jac/dkp099⟩. ⟨hal-00405448⟩

Collections

ANSES
34 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More